Invention Grant
- Patent Title: Method for diagnosing disease using adenovirus harboring trans-splicing ribozyme by molecular imaging
- Patent Title (中): 通过分子成像使携带转拼核酶的腺病毒诊断疾病的方法
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Application No.: US12522597Application Date: 2007-10-26
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Publication No.: US08541237B2Publication Date: 2013-09-24
- Inventor: In-Hoo Kim , Seong-Wook Lee , Seung-Hee Hong , Jin-Sook Jeong , Yoon-Jong Lee , Yeon-Su Lee , Haeng-Im Jung
- Applicant: In-Hoo Kim , Seong-Wook Lee , Seung-Hee Hong , Jin-Sook Jeong , Yoon-Jong Lee , Yeon-Su Lee , Haeng-Im Jung
- Applicant Address: KR
- Assignee: National Cancer Center
- Current Assignee: National Cancer Center
- Current Assignee Address: KR
- Agency: Brinks Hofer Gilson & Lione
- Priority: KR10-2007-0107828 20071025
- International Application: PCT/KR2007/005334 WO 20071026
- International Announcement: WO2009/054558 WO 20090430
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/87 ; A61K48/00
Abstract:
Disclosed herein is a composition for molecular imaging comprising a trans-splicing ribozyme coupled with an imaging reporter gene. The trans-splicing ribozyme targets a specific gene associated with a disease. Also disclosed is a molecular imaging method using the composition.
Public/Granted literature
- US20110165690A1 METHOD FOR DIAGNOSING DISEASE USING ADENOVIRUS HARBORING TRANS-SPLICING RIBOZYME BY MOLECULAR IMAGING Public/Granted day:2011-07-07
Information query
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