Invention Grant
US08541444B2 Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
有权
三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
- Patent Title: Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
- Patent Title (中): 三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
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Application No.: US13197273Application Date: 2011-08-03
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Publication No.: US08541444B2Publication Date: 2013-09-24
- Inventor: Jun Li , Jeffrey A. Robl , James J. Li , Lawrence J. Kennedy , Haixia Wang , Jie Jack Li , Chenkou Wei , Michael Galella
- Applicant: Jun Li , Jeffrey A. Robl , James J. Li , Lawrence J. Kennedy , Haixia Wang , Jie Jack Li , Chenkou Wei , Michael Galella
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Terence J. Bogie
- Main IPC: C07D471/02
- IPC: C07D471/02 ; C07D491/02 ; C07D498/02 ; A61K31/44
Abstract:
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I: or stereoisomers or pharmaceutically acceptable salts thereof, wherein G, Q, X, Y, R3, R3a, and R3b are defined herein.
Public/Granted literature
- US20110288051A1 TRIAZOLOPYRIDINE 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS Public/Granted day:2011-11-24
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