发明授权
US08541444B2 Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
有权
三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
- 专利标题： Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
- 专利标题（中）： 三唑并吡啶11-β羟基类固醇脱氢酶I型抑制剂
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申请号： US13197273申请日： 2011-08-03
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公开(公告)号： US08541444B2公开(公告)日： 2013-09-24
- 发明人: Jun Li , Jeffrey A. Robl , James J. Li , Lawrence J. Kennedy , Haixia Wang , Jie Jack Li , Chenkou Wei , Michael Galella
- 申请人： Jun Li , Jeffrey A. Robl , James J. Li , Lawrence J. Kennedy , Haixia Wang , Jie Jack Li , Chenkou Wei , Michael Galella
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Terence J. Bogie
- 主分类号： C07D471/02
- IPC分类号： C07D471/02 ; C07D491/02 ; C07D498/02 ; A61K31/44
摘要：
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I: or stereoisomers or pharmaceutically acceptable salts thereof, wherein G, Q, X, Y, R3, R3a, and R3b are defined herein.
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