发明授权
- 专利标题: Modified release dosage forms
- 专利标题(中): 改性释放剂型
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申请号: US10476530申请日: 2002-09-28
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公开(公告)号: US08545887B2公开(公告)日: 2013-10-01
- 发明人: Harry S. Sowden , David Wynn , Shun-Por Li , Der-Yang Lee , Martin Thomas
- 申请人: Harry S. Sowden , David Wynn , Shun-Por Li , Der-Yang Lee , Martin Thomas
- 申请人地址: US NJ Skillman
- 专利权人: McNeil-PPC, Inc.
- 当前专利权人: McNeil-PPC, Inc.
- 当前专利权人地址: US NJ Skillman
- 代理商 Laura A. Donnelly
- 国际申请: PCT/US02/31117 WO 20020928
- 国际公布: WO03/026629 WO 20030403
- 主分类号: A61J3/06
- IPC分类号: A61J3/06 ; A61K9/20 ; B30B11/00 ; A61K9/24 ; G06F17/30
摘要:
A dosage form comprises: (a) at least one active ingredient: (b) a core having a first surface portion upon which resides a first coating and a second surface portion which is substantially free of the first coating; and (c) a shell which resides upon at least a portion of the second surface portion, wherein the shell comprises a different material from the first coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b) a core comprising a center portion having an exterior surface and an annular portion having an exterior surface and an interior surface, wherein the annular portion interior surface is in contact with at least a portion of the center portion exterior surface, and a coating resides on at least a portion of the annular portion exterior surface; and (c) a shell which resides upon at least a portion of the exterior surface of the center portion, wherein the shell comprises a different material than the impermeable coating. In another embodiment, the dosage form comprises: (a) at least one active ingredient; (b) a core having an outer surface and a cavity which extends at least partially through the core such that the core outer surface has at least a first opening therein; (c) a first coating which resides on at least a portion of the core outer surface, wherein the first shell portion comprises a different material from the first coating; and (d) a first shell portion which is adjacent to the first opening and covers at least the first opening.
公开/授权文献
- US20040213849A1 Modified release dosage forms 公开/授权日:2004-10-28
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