发明授权
- 专利标题: Use of neuregulin-β as an indicator and/or target
- 专利标题(中): 使用神经调节蛋白-β作为指标和/或靶标
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申请号: US13035352申请日: 2011-02-25
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公开(公告)号: US08546086B2公开(公告)日: 2013-10-01
- 发明人: Andre Schrattenholz
- 申请人: Andre Schrattenholz
- 申请人地址: CH Geneva
- 专利权人: Mind-NRG SA
- 当前专利权人: Mind-NRG SA
- 当前专利权人地址: CH Geneva
- 代理机构: Rothwell, Figg, Ernst & Manbeck, P.C.
- 优先权: DE10006174 20000211; DE10006175 20000211
- 主分类号: C07K7/06
- IPC分类号: C07K7/06 ; C07K14/475 ; C07K16/22 ; G01N33/53
摘要:
The invention relates, inter alia, to the use of neuregulin-β as an indicator in a method for detecting a neuronal process. The invention furthermore relates to the use of neuregulins, preferably a neuregulin isoform having an isoelectric point in the range from pH 4.3 to 5.0, as a target for detecting and/or exerting an influence on neuronal processes, in particular for exerting an influence on long-term memory. Neuregulins, in particular neuregulin-β and also substances which exert an influence on the status, i.e. the expression and/or post-translational modification, of neuregulin-β, can therefore be used as agents for controlling the course of, treating and/or alleviating neuronal diseases, e.g. Alzheimer's disease.
公开/授权文献
- US20110244507A1 USE OF NEUREGULIN-ß AS AN INDICATOR AND/OR TARGET 公开/授权日:2011-10-06
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