发明授权
US08546401B2 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressin-dependent diseases
有权
5,6-二取代羟吲哚衍生物及其用于治疗加压素依赖性疾病的用途
- 专利标题: 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressin-dependent diseases
- 专利标题(中): 5,6-二取代羟吲哚衍生物及其用于治疗加压素依赖性疾病的用途
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申请号: US12746715申请日: 2008-12-05
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公开(公告)号: US08546401B2公开(公告)日: 2013-10-01
- 发明人: Wilfried Braje , Thorsten Oost , Astrid Netz , Wolfgang Wernet , Liliane Unger , Wilfried Hornberger , Wilfried Lubisch
- 申请人: Wilfried Braje , Thorsten Oost , Astrid Netz , Liliane Unger , Wilfried Hornberger , Wilfried Lubisch , Andrea Hager-Wernet
- 申请人地址: DE Wiesbaden
- 专利权人: AbbVie Deutschland GmbH & Co. KG
- 当前专利权人: AbbVie Deutschland GmbH & Co. KG
- 当前专利权人地址: DE Wiesbaden
- 代理机构: Michael Best & Friedrich LLP
- 代理商 Lisa V. Mueller
- 国际申请: PCT/EP2008/066935 WO 20081205
- 国际公布: WO2009/071690 WO 20090611
- 主分类号: A61K31/497
- IPC分类号: A61K31/497 ; A61K31/445 ; C07D401/00 ; C07D403/00 ; C07D405/00 ; C07D409/00 ; C07D411/00 ; C07D413/00 ; C07D417/00 ; C07D419/00 ; C07D421/00
摘要:
The present invention relates to novel 5,6-disubstituted oxindole derivatives and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising such derivatives, and to the use of such derivatives for the manufacture of a medicament, and methods of treating disorders in a subject in need thereof, such as vasopressin-dependent disorders, using 5,6-disubstituted oxindole derivatives.
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