发明授权
US08546598B2 Silane compounds having a cyclic carbon chain including an alkyne function for functionalizing solid substrates and immobilizing biological molecules on said substrates
失效
具有环状碳链的硅烷化合物，其包括用于官能化固体底物并将生物分子固定在所述基材上的炔官能团
- 专利标题： Silane compounds having a cyclic carbon chain including an alkyne function for functionalizing solid substrates and immobilizing biological molecules on said substrates
- 专利标题（中）： 具有环状碳链的硅烷化合物，其包括用于官能化固体底物并将生物分子固定在所述基材上的炔官能团
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申请号： US13257326申请日： 2010-03-16
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公开(公告)号： US08546598B2公开(公告)日： 2013-10-01
- 发明人: Aude Bernardin , Guillaume Delapierre , Antoine Hoang , Isabelle Texier-Nogues
- 申请人： Aude Bernardin , Guillaume Delapierre , Antoine Hoang , Isabelle Texier-Nogues
- 申请人地址： FR Paris
- 专利权人： Commissariat a l'Energie Atomique et aux Energies Alternatives
- 当前专利权人： Commissariat a l'Energie Atomique et aux Energies Alternatives
- 当前专利权人地址： FR Paris
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权： FR0901254 20090318
- 国际申请： PCT/FR2010/000218 WO 20100316
- 国际公布： WO2010/106243 WO 20100923
- 主分类号： C07F7/04
- IPC分类号： C07F7/04 ; C40B60/00 ; C12M1/34
摘要：
The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH2CONH—, —NHCOCH2O—, —O— or —S— group, and Z is a cycloalkyne or heterocycloalkyne with at least 8 members. The invention is particularly suitable for use in the field of medicine.
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