Systems and methods for takeoff assistance and analysis are provided. In one embodiment, a takeoff ground roll assist system for an aircraft comprises: a runway centerline estimator, wherein the runway centerline estimator generates a virtual runway centerline estimate for a runway based on coordinates for the runway from a runway database; an (Inertial Navigation System) INS Output Filter and Fault Detector wherein the filtering of navigation measurements from an on-board inertial navigation system, using a runway centerline start point as established by activation of a pilot operated start point sensor occurs, a centerline tracking estimator coupled to receive a filtered output of the on-board inertial navigation system from the INS output filter and fault detector and to receive the virtual centerline estimate from the runway centerline estimator, wherein the centerline tracking estimator generates a centerline tracking feedback signal that varies as a function of a difference between an aircraft look-ahead point and the virtual runway centerline; and a takeoff criteria evaluator coupled to the runway centerline estimator and the centerline tracking estimator, wherein the takeoff criteria evaluator estimates a lateral deviation between the aircraft and an actual runway centerline for the runway based on an estimated navigation error component, the runway database error component, and a centerline tracking error component.