Invention Grant
US08562945B2 Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof
有权
锝和铼 - 双（杂芳基）络合物及其使用方法
- Patent Title: Technetium- and rhenium-bis(heteroaryl) complexes and methods of use thereof
- Patent Title (中): 锝和铼 - 双（杂芳基）络合物及其使用方法
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Application No.: US12631312Application Date: 2009-12-04
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Publication No.: US08562945B2Publication Date: 2013-10-22
- Inventor: John W. Babich , Craig Zimmerman , John Joyal , Kevin P. Maresca , John Marquis , Genliang Lu , Jian-cheng Wang , Shawn Hillier
- Applicant: John W. Babich , Craig Zimmerman , John Joyal , Kevin P. Maresca , John Marquis , Genliang Lu , Jian-cheng Wang , Shawn Hillier
- Applicant Address: US NY Tarrytown
- Assignee: Molecular Insight Pharmaceuticals, Inc.
- Current Assignee: Molecular Insight Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Foley & Lardner LLP
- Agent Gilberto M. Villacorta; Jeffrey R. Lomprey
- Main IPC: A61K31/18
- IPC: A61K31/18 ; A61K31/4192 ; A61K31/444 ; A61K31/555 ; A61K51/04 ; C07D213/38 ; C07D403/12 ; C07F13/00 ; A61P1/00
Abstract:
Complexes of heterocyclic radionuclides are prepared based upon ligands having substituted pyridyl and imidazolyl groups. The ligands are bifunctional, having amino acid residues that may act as a linker to a bioactive molecule, and a tridentate chelator that may complex the radionuclide. The bioactive molecule may be a peptide or somatostatin.
Public/Granted literature
- US20100183509A1 TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES AND METHODS OF USE THEREOF Public/Granted day:2010-07-22
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