发明授权
- 专利标题： Peptides and methods for inhibiting G alpha protein signaling
- 专利标题（中）： 肽和抑制Gα蛋白信号传导的方法
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申请号： US13425922申请日： 2012-03-21
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公开(公告)号： US08575103B2公开(公告)日： 2013-11-05
- 发明人: Guy Le Breton , Jin-Sheng Huang , Subhashini Srinivasan , Fadi T. Khasawneh
- 申请人： Guy Le Breton , Jin-Sheng Huang , Subhashini Srinivasan , Fadi T. Khasawneh
- 申请人地址： US IL Urbana
- 专利权人： The Board of Trustees of the University of Illinois
- 当前专利权人： The Board of Trustees of the University of Illinois
- 当前专利权人地址： US IL Urbana
- 代理机构： Licata & Tyrrell, P.C.
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K38/08 ; C07K7/08 ; C07K7/06 ; C07K9/00 ; A61P7/02
摘要：
Permeable Switch Region I and II peptides in the range of 9 to 25 amino acid residues in length are provided for specifically inhibiting signaling through Gα subunits. In addition, compositions and methods for inhibiting platelet aggregation and α11bβ3 integrin activation using the Switch Region I and II peptides are provided.
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