Invention Grant
US08575173B2 Piperazinyl 3-aminopyrrolidine derivatives as a CCR2 antagonists
有权
哌嗪基3-氨基吡咯烷衍生物作为CCR2拮抗剂
- Patent Title: Piperazinyl 3-aminopyrrolidine derivatives as a CCR2 antagonists
- Patent Title (中): 哌嗪基3-氨基吡咯烷衍生物作为CCR2拮抗剂
-
Application No.: US13383104Application Date: 2010-06-11
-
Publication No.: US08575173B2Publication Date: 2013-11-05
- Inventor: Jee Woong Lim , Jong-Hoon Kim , Min-Ho Oak , Yongho Na , Youna Oh , So-Hee Kang , Jung-Ok Lee , Jung-Duk Sohn , Seung-Woo Lee
- Applicant: Jee Woong Lim , Jong-Hoon Kim , Min-Ho Oak , Yongho Na , Youna Oh , So-Hee Kang , Jung-Ok Lee , Jung-Duk Sohn , Seung-Woo Lee
- Applicant Address: KR
- Assignee: Yang Ji Chemical Co., Ltd.
- Current Assignee: Yang Ji Chemical Co., Ltd.
- Current Assignee Address: KR
- Agency: Cantor Colburn LLP
- Priority: KR10-2009-0063136 20090710
- International Application: PCT/KR2010/003790 WO 20100611
- International Announcement: WO2011/004972 WO 20110113
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D403/06
Abstract:
The present invention relates to compounds of chemical formula 1 and having CCR2 (chemokine receptor 2) antagonistic effects, and salts or isomers thereof. These compounds are very useful for treating, preventing, or relieving rheumatoid arthritis, arteriosclerosis, multiple sclerosis, asthma, and various diseases related to CCR2. wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 is the same as defined in the specification.
Public/Granted literature
- US20120190689A1 PIPERAZINYL 3-AMINOPYRROLIDINE DERIVATIVES AS A CCR2 ANTAGONIST Public/Granted day:2012-07-26
Information query
IPC分类:
