Invention Grant
US08580513B2 Methods for determining response to neoadjuvant therapy and survival using MicroRNA-10b
有权
使用MicroRNA-10b测定新辅助治疗和存活的反应的方法
- Patent Title: Methods for determining response to neoadjuvant therapy and survival using MicroRNA-10b
- Patent Title (中): 使用MicroRNA-10b测定新辅助治疗和存活的反应的方法
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Application No.: US13172047Application Date: 2011-06-29
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Publication No.: US08580513B2Publication Date: 2013-11-12
- Inventor: Lorenzo F. Sempere , Murray Korc , Meir Preis
- Applicant: Lorenzo F. Sempere , Murray Korc , Meir Preis
- Applicant Address: US NH Hanover
- Assignee: Trustees of Dartmouth College
- Current Assignee: Trustees of Dartmouth College
- Current Assignee Address: US NH Hanover
- Agency: Licata & Tyrrell, P.C.
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention provides methods for determining response to neoadjuvant therapy and metastasis-free survival in pancreatic ductal adenocarcinoma based upon the level of microRNA expression and optionally the presence of a protein cancer cell marker in biological samples such as formalin-fixed paraffin-embedded specimens using in situ hybridization and optionally an immunohistochemical assay.
Public/Granted literature
- US20120021415A1 Methods for Determining Response to Neoadjuvant Therapy and Survival Using MicroRNA-10b Public/Granted day:2012-01-26
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