Invention Grant
US08580752B2 Aromatic amides as potentiators of bioefficacy of anti-infective drugs
有权
芳香酰胺作为抗感染药物生物功效的增强剂
- Patent Title: Aromatic amides as potentiators of bioefficacy of anti-infective drugs
- Patent Title (中): 芳香酰胺作为抗感染药物生物功效的增强剂
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Application No.: US11391391Application Date: 2006-03-29
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Publication No.: US08580752B2Publication Date: 2013-11-12
- Inventor: Surrinder Koul , Jawahir Lal Koul , Subhash Chandra Taneja , Pankaj Gupta , Inshad Ali Khan , Zahid Mehmood Mirza , Ashwani Kumar , Rakesh Kamal Johri , Monika Pandita , Anita Khosa , Ashok Kumar Tikoo , Subhash Chander Sharma , Vijeshwar Verma , Ghulam Nabi Qazi
- Applicant: Surrinder Koul , Jawahir Lal Koul , Subhash Chandra Taneja , Pankaj Gupta , Inshad Ali Khan , Zahid Mehmood Mirza , Ashwani Kumar , Rakesh Kamal Johri , Monika Pandita , Anita Khosa , Ashok Kumar Tikoo , Subhash Chander Sharma , Vijeshwar Verma , Ghulam Nabi Qazi
- Applicant Address: IN New Delhi
- Assignee: Council of Scientitic and Industrial Research
- Current Assignee: Council of Scientitic and Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: IN0718/DEL/2005 20050331
- Main IPC: A61K31/70
- IPC: A61K31/70
Abstract:
The present invention relates to an aromatic substituted pentadienoic acid amides and there use in combination of specific amounts of aromatic amides i.e. 4-alkyl-5-(substituted phenyl)-2(E),4(E)-pentadienoic acid amides, its geometrical isomers or their dihydro or tetrahydro derivatives and an anti-infective drug useful in potentiating the bioefficacy of antiinfective drug. The combination of the present invention is useful in the treatment of certain infections and disease at lower concentration of anti-infectives necessary to inhibit the growth of microbial strains and may also find applications in reducing the resistance in microorganisms.
Public/Granted literature
- US20070004645A1 Aromatic amides as potentiators of bioefficacy of anti-infective drugs Public/Granted day:2007-01-04
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