发明授权
US08580818B2 Combination drug containing probucol and a tetrazolylalkoxy-dihydrocarbostyril derivative with superoxide supressant effects
失效
含有普罗布考和具有超氧化物抑制作用的四唑基烷氧基 - 二氢喹诺酮类衍生物的组合药物
- 专利标题： Combination drug containing probucol and a tetrazolylalkoxy-dihydrocarbostyril derivative with superoxide supressant effects
- 专利标题（中）： 含有普罗布考和具有超氧化物抑制作用的四唑基烷氧基 - 二氢喹诺酮类衍生物的组合药物
-
申请号： US12065619申请日： 2006-09-14
-
公开(公告)号： US08580818B2公开(公告)日： 2013-11-12
- 发明人: Ki Whan Hong , Tomohiro Yoshikawa
- 申请人： Ki Whan Hong , Tomohiro Yoshikawa
- 申请人地址： JP Tokyo
- 专利权人： Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人： Otsuka Pharmaceutical Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- 国际申请： PCT/JP2006/318675 WO 20060914
- 国际公布： WO2007/032557 WO 20070322
- 主分类号： A01N43/12
- IPC分类号： A01N43/12 ; A61K31/445
摘要：
This invention relates to a combination drug comprising a combination of a tetrazolylalkoxy-dihydrocarbostyril derivative of the formula: wherein R is cycloalkyl, A is lower alkylene, and the bond between 3- and 4-positions of carbostyril nucleus is single bond or double bond, or a salt thereof and Probucol, which is useful for preventing and treating cerebral infarction including acute cerebral infarction and chronic cerebral infarction, arteriosclerosis, renal diseases (e.g. diabetic nephropathy, renal failure, nephritis), and diabetes owing to synergistic superoxide suppressant effects of the combination.
公开/授权文献
信息查询
IPC分类:
