Invention Grant
- Patent Title: Stapled peptides and method of synthesis
- Patent Title (中): 装订肽和合成方法
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Application No.: US12561107Application Date: 2009-09-16
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Publication No.: US08586707B2Publication Date: 2013-11-19
- Inventor: Qing Lin , Mike Madden
- Applicant: Qing Lin , Mike Madden
- Applicant Address: US NY Amherst
- Assignee: The Research Foundation of State University of New York
- Current Assignee: The Research Foundation of State University of New York
- Current Assignee Address: US NY Amherst
- Agency: Hodgson Russ LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/04 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00
Abstract:
A method for preparing stapled peptides. The stapled peptides, including helical stapled peptides, are prepared according to a photochemically-based method, a [3+2] cycloaddition reaction. The helical stapled peptides exhibit increased helicity, thermal stability and cell permeability.
Public/Granted literature
- US20100093086A1 Stapled Peptides and Method of Synthesis Public/Granted day:2010-04-15
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