Invention Grant
- Patent Title: Virus vector and use thereof
- Patent Title (中): 病毒载体及其用途
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Application No.: US12450999Application Date: 2008-04-11
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Publication No.: US08586826B2Publication Date: 2013-11-19
- Inventor: Masashi Mori , Koji Dohi
- Applicant: Masashi Mori , Koji Dohi
- Applicant Address: JP Saitama
- Assignee: Japan Science and Technology Agency
- Current Assignee: Japan Science and Technology Agency
- Current Assignee Address: JP Saitama
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: JP2007-120181 20070427
- International Application: PCT/JP2008/057170 WO 20080411
- International Announcement: WO2008/136253 WO 20081113
- Main IPC: C07K14/005
- IPC: C07K14/005 ; C12N15/67 ; C12N15/40

Abstract:
It is intended to provide a polynucleotide comprising a viral base sequence, the viral base sequence containing: a first base sequence encoding a viral replication protein, and a second base sequence encoding a viral movement protein, the second base sequence being located downstream of the first base sequence and having a linking site for linking with an exogenous base sequence encoding a polypeptide to be expressed, the linking site being located downstream of the second base sequence, the second base sequence being obtained by modifying with a base sequence in a native sequence derived from a virus by insertion, substitution, or addition. By using this, a vector containing a viral base sequence is constructed, and a protein is efficiently produced without worsening growth of a host cell containing the vector.
Public/Granted literature
- US20110107466A1 VIRUS VECTOR AND USE THEREOF Public/Granted day:2011-05-05
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