Invention Grant
US08597634B2 Interferon alpha-2a modified by polyethylene glycol and methods of preparation thereof
有权
由聚乙二醇修饰的干扰素α-2a及其制备方法
- Patent Title: Interferon alpha-2a modified by polyethylene glycol and methods of preparation thereof
- Patent Title (中): 由聚乙二醇修饰的干扰素α-2a及其制备方法
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Application No.: US12676511Application Date: 2007-09-04
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Publication No.: US08597634B2Publication Date: 2013-12-03
- Inventor: Weidong Zhou , Qingjiang Xiao , Li Sun , Tiebing Wang , Bin Liu , Song Lin , Min Liu , Fenghong Yin , Lu Zhuang , Lifang Lei
- Applicant: Weidong Zhou , Qingjiang Xiao , Li Sun , Tiebing Wang , Bin Liu , Song Lin , Min Liu , Fenghong Yin , Lu Zhuang , Lifang Lei
- Applicant Address: CN Fuijan
- Assignee: Biosteed Gene Expression Tech. Co., Ltd.
- Current Assignee: Biosteed Gene Expression Tech. Co., Ltd.
- Current Assignee Address: CN Fuijan
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- International Application: PCT/CN2007/002643 WO 20070904
- International Announcement: WO2009/030065 WO 20090312
- Main IPC: A61K38/21
- IPC: A61K38/21 ; A61K38/00 ; A61K39/385 ; C07K14/56
Abstract:
The present invention relates to interferon (IFN)-α2a modified at a specific Lys residue with Y-shaped branched polyethylene glycol (PEG) derivative and the preparation thereof, as well as the use of the prepared IFN-α2a modified by PEG at a single amino acid residue in medicines.
Public/Granted literature
- US20100239532A1 INTERFERON ALPHA2A MODIFIED BY POLYETHYLENE GLYCOL, THE PREPARATION AND USE THEREOF Public/Granted day:2010-09-23
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