Invention Grant
US08597635B2 Interferon alpha-2B modified by polyethylene glycol and methods of preparation thereof
有权
由聚乙二醇改性的干扰素α-2B及其制备方法
- Patent Title: Interferon alpha-2B modified by polyethylene glycol and methods of preparation thereof
- Patent Title (中): 由聚乙二醇改性的干扰素α-2B及其制备方法
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Application No.: US12676525Application Date: 2007-09-04
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Publication No.: US08597635B2Publication Date: 2013-12-03
- Inventor: Weidong Zhou , Qingjiang Xiao , Li Sun , Tiebing Wang , Fenghong Yin , Shihong Luo , Lu Zhuang , Min Liu , Tianle Xu , Yong Zhang
- Applicant: Weidong Zhou , Qingjiang Xiao , Li Sun , Tiebing Wang , Fenghong Yin , Shihong Luo , Lu Zhuang , Min Liu , Tianle Xu , Yong Zhang
- Applicant Address: CN Fujian
- Assignee: Biosteed Gene Expression Tech. Co., Ltd.
- Current Assignee: Biosteed Gene Expression Tech. Co., Ltd.
- Current Assignee Address: CN Fujian
- Agency: Jenkins, Wilson, Taylor & Hunt, P.A.
- International Application: PCT/CN2007/002644 WO 20070904
- International Announcement: WO2009/030066 WO 20090312
- Main IPC: A61K38/21
- IPC: A61K38/21 ; A61K38/00 ; A61K39/385 ; C07K14/56
Abstract:
The present invention relates to interferon-α2b modified with Y-shaped branched polyethylene glycol (PEG) at a single Lys residue and the preparation thereof. The peglated IFN-α2b can be used for the preparation of a medicament for treating a disease, e.g. viral infections such as Hepatitis C.
Public/Granted literature
- US20110158943A1 INTERFERON ALPHA 2B MODIFIED BY POLYETHYLENE GLYCOL, THE PREPARATION AND USE THEREOF Public/Granted day:2011-06-30
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