A shut-off valve for opening and closing a cryogenic tank that has particular application for a hydrogen consuming system, such as a fuel cell system or an internal combustion engine. The shut-off valve is positioned in a supply line coupled to the cryogenic tank, and is opened by a control valve. When the control valve is actuated, hydrogen pressure from the supply line is used to open the shut-off valve. The control valve is coupled to the output line either upstream or downstream of the shut-off valve. An output of the control valve can be vented to a cathode input, an anode input or a cathode exhaust of a fuel cell stack, to an air input of an internal combustion engine or to ambient, depending on the particular application.