Invention Grant
US08598314B2 Peptide-peptidase-inhibitor conjugates and methods of making and using same
失效
肽 - 肽酶 - 抑制剂缀合物及其制备和使用方法
- Patent Title: Peptide-peptidase-inhibitor conjugates and methods of making and using same
- Patent Title (中): 肽 - 肽酶 - 抑制剂缀合物及其制备和使用方法
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Application No.: US12680539Application Date: 2008-09-26
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Publication No.: US08598314B2Publication Date: 2013-12-03
- Inventor: Soumitra S. Ghosh , Josue Alfaro-Lopez , Lawrence J. D'Souza , Odile Esther Levy , Qing Lin , Christopher J. Soares
- Applicant: Soumitra S. Ghosh , Josue Alfaro-Lopez , Lawrence J. D'Souza , Odile Esther Levy , Qing Lin , Christopher J. Soares
- Applicant Address: US CA San Diego US DE Wilmington
- Assignee: Amylin Pharmaceuticals, LLC,AstraZeneca Pharmaceuticals LP
- Current Assignee: Amylin Pharmaceuticals, LLC,AstraZeneca Pharmaceuticals LP
- Current Assignee Address: US CA San Diego US DE Wilmington
- Agency: Womble Carlyle Sandridge & Rice, LLP
- Agent Mark Pino; Alireza Behrooz
- International Application: PCT/US2008/077955 WO 20080926
- International Announcement: WO2009/042922 WO 20090402
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00
Abstract:
Peptide-peptidase inhibitor conjugate molecules and methods of manufacture thereof are disclosed. These conjugate molecules are useful as agents for the treatment and prevention of metabolic and cardiovascular diseases, disorders, and conditions. Such diseases, conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, and other diabetes-related disorders.
Public/Granted literature
- US20100286365A1 PEPTIDE-PEPTIDASE-INHIBITOR CONJUGATES AND METHODS OF MAKING AND USING SAME Public/Granted day:2010-11-11
Information query
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