Invention Grant
- Patent Title: Organic compositions to treat Beta-ENaC-related diseases
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Application No.: US13614836Application Date: 2012-09-13
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Publication No.: US08598335B2Publication Date: 2013-12-03
- Inventor: Antonin De Fougerolles , John Diener , Emma Hickman , Gregory Hinkle , Stuart Milstein , Anne-Marie Pulichino , Andrew Griffin Sprague
- Applicant: Antonin De Fougerolles , John Diener , Emma Hickman , Gregory Hinkle , Stuart Milstein , Anne-Marie Pulichino , Andrew Griffin Sprague
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Frank Wu
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02 ; A61K48/00
Abstract:
The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.
Public/Granted literature
- US20130012571A1 Organic Compositions to Treat Beta-ENaC-Related Diseases Public/Granted day:2013-01-10
Information query
