Invention Grant
- Patent Title: Benzodioxole piperidine compounds
- Patent Title (中): 苯并二氧杂环戊烯哌啶化合物
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Application No.: US13405392Application Date: 2012-02-27
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Publication No.: US08598357B2Publication Date: 2013-12-03
- Inventor: Rosa Maria Rodriguez Sarmiento , Juergen Wichmann
- Applicant: Rosa Maria Rodriguez Sarmiento , Juergen Wichmann
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Priority: EP11156787 20110303
- Main IPC: C07D211/22
- IPC: C07D211/22 ; A61K31/445

Abstract:
The present invention is concerned with novel dual modulators of the 5-HT2A and D3 receptors of formula (I) wherein n, Y, R1, R2, R3, and R4 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. Further the present invention is concerned with the manufacture of the compounds of formula (I), pharmaceutical compositions containing them and their use as pharmaceuticals.
Public/Granted literature
- US20120225868A1 NOVEL BENZODIOXOLE PIPERIDINE COMPOUNDS Public/Granted day:2012-09-06
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