- 专利标题： Compounds for the treatment of proliferative disorders
-
申请号： US13558886申请日： 2012-07-26
-
公开(公告)号： US08598366B2公开(公告)日： 2013-12-03
- 发明人: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人： Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人地址： US MA Lexington
- 专利权人： Synta Pharmaceuticals Corporation
- 当前专利权人： Synta Pharmaceuticals Corporation
- 当前专利权人地址： US MA Lexington
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis; Wei Song
- 主分类号： C07D261/02
- IPC分类号： C07D261/02
摘要：
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
公开/授权文献
- US20120289483A1 COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS 公开/授权日：2012-11-15
信息查询
