An air interface synchronization method is provided. The method includes that: a home-eNodeB which is not synchronized with an eNodeB, intercepts a synchronization subframe transmitted from the eNodeB and/or the home-eNodeB which was already synchronized with the eNodeB, a synchronization reference base station is selected from the base station which transmits the intercepted synchronization subframe, wherein the synchronization subframe includes a special synchronization channel for broadcasting synchronization sequence; the synchronization sequence is obtained, which is broadcasted in the special synchronization channel of the synchronization subframe transmitted by the synchronization reference station, and the synchronization with the synchronization base station is performed according to the synchronization sequence. Also, an air interface synchronization system, an eNodeB and a home-eNodeB are provided. The problem in prior art that the source is wasted in the process of synchronization is solved according to the method, the system, the eNodeB and the home-eNodeB.