发明授权
US08609622B2 C-aryl glucoside derivatives, preparation process and pharmaceutical use thereof
有权
C-芳基葡糖苷衍生物，其制备方法和药物用途
- 专利标题： C-aryl glucoside derivatives, preparation process and pharmaceutical use thereof
- 专利标题（中）： C-芳基葡糖苷衍生物，其制备方法和药物用途
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申请号： US13813045申请日： 2011-06-30
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公开(公告)号： US08609622B2公开(公告)日： 2013-12-17
- 发明人: Fanglong Yang , Peng Cho Tang , Qing Dong , Wangyang Tu , Jiang Fan , Dongliang Guan , Guangyuan Shen , Yang Wang , Jijun Yuan , Limin Zhang
- 申请人： Fanglong Yang , Peng Cho Tang , Qing Dong , Wangyang Tu , Jiang Fan , Dongliang Guan , Guangyuan Shen , Yang Wang , Jijun Yuan , Limin Zhang
- 申请人地址： CN Shanghai CN Lianyungang, Jiangsu
- 专利权人： Shanghai Hengrui Pharmaceutical Co., Ltd.,Jiangsu Hengrui Medicine Co., Ltd.
- 当前专利权人： Shanghai Hengrui Pharmaceutical Co., Ltd.,Jiangsu Hengrui Medicine Co., Ltd.
- 当前专利权人地址： CN Shanghai CN Lianyungang, Jiangsu
- 代理机构： Panitch Schwarze Belisario & Nadel LLP
- 优先权： CN201010249618 20100810; CN201010589606 20101206
- 国际申请： PCT/CN2011/076680 WO 20110630
- 国际公布： WO2012/019496 WO 20120216
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07H15/04
摘要：
C-aryl glucoside derivatives, preparation processes and pharmaceutical uses thereof are disclosed. In particular, C-aryl glucoside derivatives represented by formula (I), with each substituent defined in the application, pharmaceutically acceptable salts or stereoisomers thereof, their preparation methods, and pharmaceutical compositions containing the derivatives as well as their uses as therapeutic agents, particularly as sodium-dependent glucose cotransporter (SGLT)-1 inhibitors, are disclosed.
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