Invention Grant
US08623600B2 Methods and compositions for identifying inhibitors of MutSα or MutSβ interaction with MutLα
有权
用于鉴定MutSalpha或MutSbeta与MutLalpha相互作用的抑制剂的方法和组合物
- Patent Title: Methods and compositions for identifying inhibitors of MutSα or MutSβ interaction with MutLα
- Patent Title (中): 用于鉴定MutSalpha或MutSbeta与MutLalpha相互作用的抑制剂的方法和组合物
-
Application No.: US13025897Application Date: 2011-02-11
-
Publication No.: US08623600B2Publication Date: 2014-01-07
- Inventor: Paul L. Modrich , Ravi R. Iyer , Anna Pluciennik , Miaw-Sheue Tsai
- Applicant: Paul L. Modrich , Ravi R. Iyer , Anna Pluciennik , Miaw-Sheue Tsai
- Applicant Address: US NC Durham US DC Washington
- Assignee: Duke University,The United States of America, as Represented by the Secretary of Energy
- Current Assignee: Duke University,The United States of America, as Represented by the Secretary of Energy
- Current Assignee Address: US NC Durham US DC Washington
- Agency: Andrus, Sceales, Starke & Sawall, LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/04
Abstract:
Disclosed are methods and kits for screening potential inhibitors of MutSβ by screening agents for the ability to selectively inhibit interaction between MutSβ and MutLα. Also disclosed are kits for performing the methods of the invention.
Public/Granted literature
Information query
