发明授权
- 专利标题: Sustained drug-releasing stent
- 专利标题(中): 持续放药支架
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申请号: US13492290申请日: 2012-06-08
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公开(公告)号: US08641756B2公开(公告)日: 2014-02-04
- 发明人: Ikuo Omura , Zhen Yu Jin , Shuzo Yamashita , Hiroo Iwata , Akira Mochizuki
- 申请人: Ikuo Omura , Zhen Yu Jin , Shuzo Yamashita , Hiroo Iwata , Akira Mochizuki
- 申请人地址: JP Okayama JP Tokyo JP Hiroshima JP Kyoto
- 专利权人: Japan Stent Technology Co., Ltd.,Tokai University Educational System,Toyo Advanced Technologies Co., Ltd.,Hiroo Iwata Institute for Frontier Medical Sciences, Kyoto University
- 当前专利权人: Japan Stent Technology Co., Ltd.,Tokai University Educational System,Toyo Advanced Technologies Co., Ltd.,Hiroo Iwata Institute for Frontier Medical Sciences, Kyoto University
- 当前专利权人地址: JP Okayama JP Tokyo JP Hiroshima JP Kyoto
- 优先权: JP2007-228788 20070904
- 主分类号: A61F2/82
- IPC分类号: A61F2/82
摘要:
A stent includes a stent body of a cylindrical configuration having outer and inner surfaces, a first coated layer coating at least the outer surface, and a second coated layer coating substantially completely over the first coated layer. The first coated layer is prepared of a first composition comprising a polymer and a vascular intimal hyperplasia inhibitor (preferably argatroban) of a kind, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the inhibitor being within the range of 8:2 to 3:7. On the other hand, the second coated layer is prepared of a polymer alone or a second composition comprising a polymer and a drug, the weight compositional ratio of the drug to 80% by weight of the polymer being less than 20% by weight.
公开/授权文献
- US20120310329A1 SUSTAINED DRUG-RELEASING STENT 公开/授权日:2012-12-06
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