发明授权
- 专利标题： Treatment of immune disorders with anti-CD70 antibody
- 专利标题（中）： 用抗CD70抗体治疗免疫疾病
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申请号： US12016814申请日： 2008-01-18
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公开(公告)号： US08647624B2公开(公告)日： 2014-02-11
- 发明人: Che-Leung Law , Julie McEarchern , Alan F. Wahl
- 申请人： Che-Leung Law , Julie McEarchern , Alan F. Wahl
- 申请人地址： US WA Bothel
- 专利权人： Seattle Genetics, Inc.
- 当前专利权人： Seattle Genetics, Inc.
- 当前专利权人地址： US WA Bothel
- 代理机构： Alston & Bird LLP
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/28
摘要：
Disclosed are CD70 binding agents, such as anti-CD70 antibodies and derivatives, that induce a cytotoxic, cytostatic or immunosuppressive without conjugation to a therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody or derivative. Also disclosed are methods for the treatment and prevention of CD70-expressing cancers and immunological disorders comprising administering to a subject the CD70-binding agent.
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