发明授权
- 专利标题: Composition for external use and method for producing the same
- 专利标题(中): 外用组合物及其制造方法
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申请号: US13514623申请日: 2010-12-03
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公开(公告)号: US08647650B2公开(公告)日: 2014-02-11
- 发明人: Masayoshi Miyamoto , Tomomi Kuromiya , Daisuke Suzuki
- 申请人: Masayoshi Miyamoto , Tomomi Kuromiya , Daisuke Suzuki
- 申请人地址: FR Neuilly sur Seine
- 专利权人: Chanel Parfums Beaute
- 当前专利权人: Chanel Parfums Beaute
- 当前专利权人地址: FR Neuilly sur Seine
- 代理机构: Young & Thompson
- 优先权: JP2009-281969 20091211
- 国际申请: PCT/EP2010/068852 WO 20101203
- 国际公布: WO2011/069915 WO 20110616
- 主分类号: A61K8/02
- IPC分类号: A61K8/02 ; A61K9/14
摘要:
A method for producing a composition for external use containing a physiologically acceptable salt of a tranexamate as an active ingredient, which is dispersed in the composition in the state of fine particles, includes dissolving a physiologically acceptable salt of the tranexamate in a solvent to prepare a solution, to which a salting-out agent is added to precipitate the salt. Such salt is so dispersed in a composition for external use in the state of fine particles, that the tranexamate salt can be mixed without using a large amount of an oil component to obtain a composition for external use affording excellent feel of use and stability.
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