Invention Grant
- Patent Title: Solid polymer delivery compositions and methods for use thereof
- Patent Title (中): 固体聚合物输送组合物及其使用方法
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Application No.: US11525491Application Date: 2006-09-21
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Publication No.: US08652504B2Publication Date: 2014-02-18
- Inventor: Hong Li , William G. Turnell , Yumin Yuan , Geoffrey C. Landis , Ryan L. Knoy
- Applicant: Hong Li , William G. Turnell , Yumin Yuan , Geoffrey C. Landis , Ryan L. Knoy
- Applicant Address: US CA San Diego
- Assignee: Medivas, LLC
- Current Assignee: Medivas, LLC
- Current Assignee Address: US CA San Diego
- Agency: Nixon & Vanderhye P.C.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K39/395 ; C08F20/00 ; A61F2/02

Abstract:
The present invention provides an implantable solid polymer delivery composition that can be formulated to release a bioactive agent to an interior body site at a controlled rate over an extended period of time by adjusting the various components of the composition. The controlled delivery of the composition avoids an initial drug spike, resulting in a smooth delivery profile over time. Polymer layers in the composition can be porous and are both biodegradable in water and body enzymes and biocompatible. Methods of making the implantable solid polymer compositions and methods of delivering a bioactive agent at a controlled rate to an interior body site are also provided.
Public/Granted literature
- US20070077272A1 Solid polymer delivery compositions and methods for use thereof Public/Granted day:2007-04-05
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