Invention Grant
- Patent Title: Methods for preparing anti-viral nucleotide analogs
- Patent Title (中): 制备抗病毒核苷酸类似物的方法
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Application No.: US13573666Application Date: 2012-10-03
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Publication No.: US08664386B2Publication Date: 2014-03-04
- Inventor: Denise A. Colby , Andrew Anthony Martins , Benjamin James Roberts , Robert William Scott , Nicole S. White
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Main IPC: C07F9/06
- IPC: C07F9/06
Abstract:
Methods for isolating 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine (compound 16): a method for preparing, in high diastereomeric purity, intermediate compounds 13 and 15: and a method for preparing intermediate compound 12: 9-{(R)-2-[((S)-{[(S)-1-(isopropoxycarbonyl)ethyl]amino}phenoxyphosphinyl)methoxy]propyl}adenine has anti-viral properties.
Public/Granted literature
- US20130090473A1 Methods for preparing anti-viral nucleotide analogs Public/Granted day:2013-04-11
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