发明授权
- 专利标题： Cytotoxin compounds and methods of isolation
- 专利标题（中）： 细胞毒素化合物和分离方法
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申请号： US12066938申请日： 2006-09-18
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公开(公告)号： US08669376B2公开(公告)日： 2014-03-11
- 发明人: Bill Baker , Thushara Diyabalanage , James B. McClintock , Charles D. Amsler
- 申请人： Bill Baker , Thushara Diyabalanage , James B. McClintock , Charles D. Amsler
- 申请人地址： US FL Tampa US AL Birmingham
- 专利权人： University of South Florida,The UAB Research Foundation
- 当前专利权人： University of South Florida,The UAB Research Foundation
- 当前专利权人地址： US FL Tampa US AL Birmingham
- 代理机构： Saliwanchik, Lloyd & Eisenschenk
- 国际申请： PCT/US2006/036484 WO 20060918
- 国际公布： WO2007/035734 WO 20070329
- 主分类号： C07D313/00
- IPC分类号： C07D313/00 ; C12N9/99 ; A61K31/335 ; A61P35/00
摘要：
The present invention concerns groups of compounds derived from tunicates of the Synoicum species, as well as to pharmaceutical compositions comprising these compounds, and uses thereof. Extracts from tunicates show selective toxicity against several different cancer cell lines in the NCI 60 cell line panel. These compounds are useful in the effective treatment of cancers, particularly malignant melanomas, colon cancer, and renal cancer cell lines.
公开/授权文献
- US20090192215A1 Cytotoxin Compounds and Methods of Isolation 公开/授权日：2009-07-30
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