Invention Grant
US08673314B2 Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
有权
通过循环给药产生的针对流感病毒的单克隆抗体及其应用
- Patent Title: Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof
- Patent Title (中): 通过循环给药产生的针对流感病毒的单克隆抗体及其应用
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Application No.: US12788103Application Date: 2010-05-26
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Publication No.: US08673314B2Publication Date: 2014-03-18
- Inventor: Adolfo Garcia-Sastre , Peter Palese , Taia T. Wang
- Applicant: Adolfo Garcia-Sastre , Peter Palese , Taia T. Wang
- Applicant Address: US NY New York
- Assignee: Mount Sinai School of Medicine
- Current Assignee: Mount Sinai School of Medicine
- Current Assignee Address: US NY New York
- Agency: Jones Day
- Main IPC: A61K39/145
- IPC: A61K39/145 ; A61K39/42
Abstract:
Provided herein are methods of producing neutralizing monoclonal antibodies, by cyclical immunization, that cross-react with strains of Influenza virus of the same subtype or different subtypes. Also provided herein are compositions comprising such antibodies and methods of using such antibodies to diagnose, prevent or treat Influenza virus disease.
Public/Granted literature
- US20110027270A1 MONOCLONAL ANTIBODIES AGAINST INFLUENZA VIRUS GENERATED BY CYCLICAL ADMINISTRATION AND USES THEREOF Public/Granted day:2011-02-03
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