Invention Grant
US08673855B2 Phosphatidylinositol 3-kinases activity regulator including the fifth zinc finger domain of FOG2
有权
磷脂酰肌醇3-激酶活性调节剂包括FOG2的第五锌指结构域
- Patent Title: Phosphatidylinositol 3-kinases activity regulator including the fifth zinc finger domain of FOG2
- Patent Title (中): 磷脂酰肌醇3-激酶活性调节剂包括FOG2的第五锌指结构域
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Application No.: US13703006Application Date: 2010-06-08
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Publication No.: US08673855B2Publication Date: 2014-03-18
- Inventor: Vic Narry Kim , Jung Hyun Lee
- Applicant: Vic Narry Kim , Jung Hyun Lee
- Applicant Address: KR Seoul
- Assignee: Seoul National University R&DB Foundation
- Current Assignee: Seoul National University R&DB Foundation
- Current Assignee Address: KR Seoul
- Agency: The PL Law Group, PLLC
- International Application: PCT/KR2010/003667 WO 20100608
- International Announcement: WO2011/155643 WO 20111215
- Main IPC: C07K14/47
- IPC: C07K14/47
Abstract:
The present invention relates to a phosphatidylinositol 3-kinases activity regulator which include the fifth zinc finger domain of FOG2 and which, more specifically, can induce cancer cells to die due to the inclusion of the fifth zinc finger domain of FOG2. Since the death of cancer cells is induced by suppressing the transfer of PI3K signals, the fifth zinc finger domain of FOG2 according to the present invention can be suitably use as a composition for the prevention and treatment of PI3K-related diseases.
Public/Granted literature
- US20130116185A1 PHOSPHATIDYLINOSITOL 3-KINASES ACTIVITY REGULATOR INCLUDING THE FIFTH ZINC FINGER DOMAIN OF FOG2 Public/Granted day:2013-05-09
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