发明授权
- 专利标题： Methods of monitoring angiogenesis and metastasis in three dimensional co-cultures
- 专利标题（中）： 监测三维共培养血管生成和转移的方法
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申请号： US12802666申请日： 2010-06-10
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公开(公告)号： US08679836B2公开(公告)日： 2014-03-25
- 发明人: Enrique Zudaire , Frank Cuttitta , Changge Fang
- 申请人： Enrique Zudaire , Frank Cuttitta , Changge Fang
- 申请人地址： US DC Washington
- 专利权人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Klarquist Sparkman, LLP
- 主分类号： C12N5/07
- IPC分类号： C12N5/07 ; C12N5/00 ; C12N5/02 ; C12N1/00
摘要：
This disclosure relates to fluorescent cell lines and to the use of such cell lines in monitoring cellular activity, such as angiogenesis. This disclosure further relates to the use of such cell lines in a three-dimensional cell culture to monitor angiogenic and metastatic potential of tumor cells and selecting personalized therapeutics for treatment of cancer.
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