Invention Grant
- Patent Title: Macrocyclic derivatives for the treatment of diseases
- Patent Title (中): 用于治疗疾病的大环衍生物
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Application No.: US13786106Application Date: 2013-03-05
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Publication No.: US08680111B2Publication Date: 2014-03-25
- Inventor: Simon Bailey , Benjamin Joseph Burke , Michael Raymond Collins , Jingrong Jean Cui , Judith Gail Deal , Robert Louis Hoffman , Qinhua Huang , Ted William Johnson , Robert Steven Kania , John Charles Kath , Phuong Thi Quy Le , Michele Ann McTigue , Cynthia Louise Palmer , Paul Francis Richardson , Neal William Sach
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Leslie A. Robinson
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; A01N43/02 ; A61K31/335 ; C07D471/00 ; C07D491/00 ; C07D498/00 ; C07D513/00 ; C07D515/00 ; C07D313/00

Abstract:
The invention relates to compounds of formula (Φ) as further defined herein and to the pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising such compounds and salts, and to the uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma kinase (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders, such as cancer.
Public/Granted literature
- US20130252961A1 MACROCYCLIC DERIVATIVES FOR THE TREATMENT OF DISEASES Public/Granted day:2013-09-26
Information query
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