发明授权
US08680260B2 18F-labeled azide compound, reagent for 18F-labeling and method for 18F-labeling of alkyne compound using same
失效
18F标记的叠氮化合物，用于18F标记的试剂和使用其的18E-标记炔化合物的方法
- 专利标题： 18F-labeled azide compound, reagent for 18F-labeling and method for 18F-labeling of alkyne compound using same
- 专利标题（中）： 18F标记的叠氮化合物，用于18F标记的试剂和使用其的18E-标记炔化合物的方法
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申请号： US13320421申请日： 2010-05-14
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公开(公告)号： US08680260B2公开(公告)日： 2014-03-25
- 发明人: Yasuyoshi Watanabe , Masaaki Suzuki , Hisashi Doi , Takeshi Kuboyama , Satoshi Obika , Takeshi Imanishi
- 申请人： Yasuyoshi Watanabe , Masaaki Suzuki , Hisashi Doi , Takeshi Kuboyama , Satoshi Obika , Takeshi Imanishi
- 申请人地址： JP Wako-Shi
- 专利权人： Riken
- 当前专利权人： Riken
- 当前专利权人地址： JP Wako-Shi
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： JP2009-118505 20090515
- 国际申请： PCT/JP2010/058217 WO 20100514
- 国际公布： WO2010/131745 WO 20101118
- 主分类号： C07H21/00
- IPC分类号： C07H21/00
摘要：
The present invention provides an 18F-labeled azide compound usable in the Huisgen reaction which enables 18F-labeling although only a small quantity of alkyne compound is available as a counterpart substrate, more specifically the 18F-labeled azide compound enabling the PET to be applied to peptides or oligonucleotides and enabling the 18F-labeling of any sites of oligonucleotide other than the 5′ end or 3′ end thereof, a reagent for 18F-labeling, and a method for 18F-labeling of an alkyne compound using the same.
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