发明授权
- 专利标题： Vaccine formulation potentiated by the combination of DNA and an antigen
- 专利标题（中）： 通过DNA和抗原的组合增强疫苗制剂
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申请号： US12430534申请日： 2009-04-27
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公开(公告)号： US08691234B2公开(公告)日： 2014-04-08
- 发明人: Santiago Duenas Carrera , Juan Morales Grillo , Liz Alvarez-Lajonchere Ponce de Leon , Alexis Musacchio Lasa , Rolando Pajon Feyt , Ariel Vina Rodriguez , Julio C. Alvarez Obregon , Nelson Acosta Rivero , Gillian Martinez Donato
- 申请人： Santiago Duenas Carrera , Juan Morales Grillo , Liz Alvarez-Lajonchere Ponce de Leon , Alexis Musacchio Lasa , Rolando Pajon Feyt , Ariel Vina Rodriguez , Julio C. Alvarez Obregon , Nelson Acosta Rivero , Gillian Martinez Donato
- 申请人地址： CU Ciudad de la Habana
- 专利权人： Centro de Ingenieria Genetica y Biotecnologia
- 当前专利权人： Centro de Ingenieria Genetica y Biotecnologia
- 当前专利权人地址： CU Ciudad de la Habana
- 代理机构： Hoffmann & Baron LLP
- 优先权： CU2001-0171 20010716
- 主分类号： A61K39/00
- IPC分类号： A61K39/00
摘要：
Formulation of vaccine antigens, containing as main components: a—) one or several DNA expressing one or several proteins in the immunized individuals and b—) a viral antigen, in appropriate proportions. Development of new formulations, minimizing the number of components that enhance and diversify the spectrum of immune response against different pathogenic entities and generating combined vaccines against pathogens.These formulations can be applied in the pharmaceutical industry for preventive and-or therapeutic use in human.
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