Invention Grant
- Patent Title: Diphosphine ligand and transition metal complex using the same
- Patent Title (中): 二膦配体和过渡金属络合物使用它们
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Application No.: US11992167Application Date: 2006-09-20
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Publication No.: US08691718B2Publication Date: 2014-04-08
- Inventor: Mitsuhisa Yamano , Mitsutaka Goto , Shinji Kawaguchi , Masatoshi Yamada , Jun-ichi Kawakami
- Applicant: Mitsuhisa Yamano , Mitsutaka Goto , Shinji Kawaguchi , Masatoshi Yamada , Jun-ichi Kawakami
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2005-272599 20050920
- International Application: PCT/JP2006/319095 WO 20060920
- International Announcement: WO2007/034975 WO 20070329
- Main IPC: B01J31/24
- IPC: B01J31/24 ; C07F15/00 ; C07F1/08

Abstract:
The present invention provides a novel ligand represented by the following formula and a novel transition metal complex having the ligand, which shows superior enantioselectivity and catalytic efficiency, particularly high catalyst activity, in various asymmetric synthesis reactions.A transition metal complex having, as a ligand, a compound represented by the formula wherein R4 is a hydrogen atom or a C1-6 alkyl group optionally having substituent(s), and R5 and R6 are each a C1-6 alkyl group optionally having substituent(s), or the formula is a group represented by the formula wherein ring B is a 3- to 8-membered ring optionally having substituent(s).
Public/Granted literature
- US20090270635A1 Diphosphine Ligand and Transition Metal Complex Using the Same Public/Granted day:2009-10-29
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