发明授权
US08697378B2 Method and kit for quantitative determination for small, dense particle low density lipoproteins
有权
用于定量测定小，致密颗粒低密度脂蛋白的方法和试剂盒
- 专利标题： Method and kit for quantitative determination for small, dense particle low density lipoproteins
- 专利标题（中）： 用于定量测定小，致密颗粒低密度脂蛋白的方法和试剂盒
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申请号： US12065125申请日： 2006-08-31
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公开(公告)号： US08697378B2公开(公告)日： 2014-04-15
- 发明人: Yasuki Itoh
- 申请人： Yasuki Itoh
- 申请人地址： JP Tokyo
- 专利权人： Denka Seiken Co., Ltd.
- 当前专利权人： Denka Seiken Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Foley & Lardner LLP
- 优先权： JP2005-252091 20050831
- 国际申请： PCT/JP2006/317243 WO 20060831
- 国际公布： WO2007/026829 WO 20070308
- 主分类号： C12Q1/60
- IPC分类号： C12Q1/60
摘要：
A rapid and convenient method capable of performing fractional measurement of small, dense LDLs without pretreatment of a specimen, which is adaptable for an autoanalyzer, is provided. A method for quantitatively determining small, dense LDL cholesterol is provided, which comprises adding enzymes for cholesterol measurement to a test sample in the presence of a polyoxyethylene-polyoxypropylene copolymer or a derivative thereof, causing the polyoxyethylene-polyoxypropylene copolymer or the derivative thereof to selectively act on small, dense LDLs among lipoproteins, and then measuring the amount of cholesterol generated.
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