Invention Grant
US08697727B2 N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
有权
N-取代 - 杂环烷氧基苯甲酰胺化合物及其使用方法
- Patent Title: N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
- Patent Title (中): N-取代 - 杂环烷氧基苯甲酰胺化合物及其使用方法
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Application No.: US13185030Application Date: 2011-07-18
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Publication No.: US08697727B2Publication Date: 2014-04-15
- Inventor: Rajinder Singh , Jiaxin Yu , Hui Hong , Sambaiah Thota , Xiang Xu , Ihab S. Darwish
- Applicant: Rajinder Singh , Jiaxin Yu , Hui Hong , Sambaiah Thota , Xiang Xu , Ihab S. Darwish
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Agent Travis Young
- Main IPC: A01N43/40
- IPC: A01N43/40 ; A61K31/445 ; C07D211/00
Abstract:
The present invention provides N-substituted-heterocycloalkyloxybenzamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment of the invention is a compound having the structure in which R1, R2, R3, R4, T, n, w and x are as described herein. In certain embodiments of the invention, a compound of the present invention activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.
Public/Granted literature
- US20110306767A1 N-Substituted-Heterocycloalkyloxybenzamide Compounds and Methods of Use Public/Granted day:2011-12-15
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