发明授权
- 专利标题: Phosphodiesterase inhibitors and uses thereof
- 专利标题(中): 磷酸二酯酶抑制剂及其用途
-
申请号: US13167540申请日: 2011-06-23
-
公开(公告)号: US08697875B2公开(公告)日: 2014-04-15
- 发明人: Yan Feng , Ottavio Arancio , Shixian Deng , Donald W. Landry
- 申请人: Yan Feng , Ottavio Arancio , Shixian Deng , Donald W. Landry
- 申请人地址: US NY New York
- 专利权人: The Trustees of Columbia University in the City of New York
- 当前专利权人: The Trustees of Columbia University in the City of New York
- 当前专利权人地址: US NY New York
- 代理机构: Wilmer, Cutler, Pickering, Hale & Dorr LLP
- 优先权: WOPCT/US2009/039129 20090401
- 主分类号: A61P25/00
- IPC分类号: A61P25/00 ; A61P25/28 ; C07D215/44
摘要:
The invention provides for compounds that are phosphodiesterase inhibitors. The invention further provides for a method for screening compounds that bind to and modulate a phosphosdiesterase protein. The invention also provides methods for treating conditions associated with accumulated amyloid-beta peptide deposit accumulations by administering a phosphodiesterase-binding compound to a subject.
公开/授权文献
- US20120076732A1 PHOSPHODIESTERASE INHIBITORS AND USES THEREOF 公开/授权日:2012-03-29
信息查询