发明授权
- 专利标题: Purification of taxanes
- 专利标题(中): 紫杉烷的纯化
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申请号: US12705247申请日: 2010-02-12
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公开(公告)号: US08703982B2公开(公告)日: 2014-04-22
- 发明人: Brian A. Bucher , Edward M. Desimone, III , Roland R. Franke , Rex T. Gallagher , Barry J. Hand , Christopher D. Howe , James A. Johnson , John S. Juchum , Marc A. Plante , T. G. Sambandam , Dong S. Yang
- 申请人: Brian A. Bucher , Edward M. Desimone, III , Roland R. Franke , Rex T. Gallagher , Barry J. Hand , Christopher D. Howe , James A. Johnson , John S. Juchum , Marc A. Plante , T. G. Sambandam , Dong S. Yang
- 申请人地址: US TX San Antonio
- 专利权人: Phyton Holdings LLC
- 当前专利权人: Phyton Holdings LLC
- 当前专利权人地址: US TX San Antonio
- 代理机构: Fulbright & Jaworski LLP
- 主分类号: C07D305/00
- IPC分类号: C07D305/00 ; C07D407/00
摘要:
Disclosed is a method of crystallizing a taxane comprising combining the taxane and methylene chloride to obtain a solution and adding an anti-solvent to the solution to obtain a crystalline taxane, wherein the anti-solvent is selected from the group consisting of hexane and heptane.
公开/授权文献
- US20100145080A1 PURIFICATION OF TAXANES 公开/授权日:2010-06-10
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