An open framework system for both heterogeneous computing and service integration includes Wrappers both registering and administrating services by service having similar function, a framework transferring an execution result of a service to the applications after discovering the service through the Wrappers and invocating the service in case of receiving a message requesting the service from the applications, a message broker transferring messages between the applications and the framework, and an external module converting the protocols for meeting specification of the Wrapper for an existing service in an open framework system for both heterogeneous computing and service integration efficiently establishing USS (Ubiquitous Smart Space) by systematically integrating services of various protocols using in a plurality of applications under ubiquitous environment.