发明授权
- 专利标题: Genetic test for the identification of carriers of complex vertebral malformations in cattle
- 专利标题(中): 鉴定牛复杂脊椎畸形的载体的遗传试验
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申请号: US12571772申请日: 2009-10-01
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公开(公告)号: US08715925B2公开(公告)日: 2014-05-06
- 发明人: Christian Bendixen , Søren Svendsen , Helle Jensen , Frank Panitz , Anders Aasberg , Lars-Erik Holm , Per Horn , Anette Høj , Bo Thomsen , Mette Jeppesen , Vivi Hunnicke Nielsen , Marc Jonker
- 申请人: Christian Bendixen , Søren Svendsen , Helle Jensen , Frank Panitz , Anders Aasberg , Lars-Erik Holm , Per Horn , Anette Høj , Bo Thomsen , Mette Jeppesen , Vivi Hunnicke Nielsen , Marc Jonker
- 申请人地址: DK Aarhus C DK Randers SO
- 专利权人: Aarhus Universitet,Viking Genetics FMBA
- 当前专利权人: Aarhus Universitet,Viking Genetics FMBA
- 当前专利权人地址: DK Aarhus C DK Randers SO
- 代理机构: McLane, Graf, Raulerson & Middleton, PA
- 优先权: DK200001717 20001116; DK200100765 20010515
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C12Q1/68
摘要:
Genetic markets for identifying bovine carriers of complex vertebral malformation (CVM) disease gene are described. The genetic markers, including the microsatellite markers, BM4129, INRAA003, BMS2790, ILSTS029, INRA123, BM220, HUJ246, BMS862, BMS937, BL1048, BMS2095 and BMS1266 and the bovine SLC35A3 gene, are located on bovine chromosome BTA3. The G/T polymorphism at position 559 of the bovine SLC35A3 gene is identified as being causative and diagnostic for CVM in cattle.