发明授权
US08716253B2 Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
有权
通过位置化学变化调节免疫刺激性寡核苷酸类似物的免疫刺激活性
- 专利标题： Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
- 专利标题（中）： 通过位置化学变化调节免疫刺激性寡核苷酸类似物的免疫刺激活性
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申请号： US10694075申请日： 2003-10-27
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公开(公告)号： US08716253B2公开(公告)日： 2014-05-06
- 发明人: Ekambar R. Kandimalla , Qiuyan Zhao , Dong Yu , Sudhir Agrawal
- 申请人： Ekambar R. Kandimalla , Qiuyan Zhao , Dong Yu , Sudhir Agrawal
- 申请人地址： US MA Cambridge
- 专利权人： Idera Pharmaceuticals, Inc.
- 当前专利权人： Idera Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C07H21/02 ; A01N43/04 ; A61K39/00 ; A61K39/38
摘要：
The invention relates to the therapeutic use of oligonucleotides or oligonucleotide analogs as immunostimulatory agents in immunotherapy applications. The invention provides methods for enhancing the immune response caused by immunostimulatory oligonucleotide compounds.
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