发明授权
- 专利标题: Antiprotozoal compound derived from coelenterata
- 专利标题(中): 来自肠杆菌的抗原虫化合物
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申请号: US13583789申请日: 2011-03-10
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公开(公告)号: US08722909B2公开(公告)日: 2014-05-13
- 发明人: Yoichi Nakao , Shintaro Ishigami , Yasuyuki Goto , Shin-ichiro Kawazu , Noboru Inoue
- 申请人: Yoichi Nakao , Shintaro Ishigami , Yasuyuki Goto , Shin-ichiro Kawazu , Noboru Inoue
- 申请人地址: JP Tokyo
- 专利权人: Waseda University
- 当前专利权人: Waseda University
- 当前专利权人地址: JP Tokyo
- 代理机构: Fox Rothschild, LLP
- 代理商 Robert J. Sacco
- 优先权: JP2010-055150 20100311
- 国际申请: PCT/JP2011/055715 WO 20110310
- 国际公布: WO2011/111804 WO 20110915
- 主分类号: C07D311/00
- IPC分类号: C07D311/00
摘要:
The object is to develop an antiprotozoal remedy having a novel mechanism of action. Provided is a compound represented by a chemical formula (1), a prodrug or a pharmaceutically acceptable salt thereof, wherein within the formula (1), R1 represents R10— of formula (4) or R20— of formula (5); R2 represents CHO—, etc.; R3 represents a hydrogen atom, CH3—C(═O)—, etc.; R4 represents a hydrogen atom, CH3—C(═O)—, etc.; each of R11 and R12 independently represents a hydrogen atom, a methyl group, etc.; R13 represents —CH2—, —CH(—OH)— or —C(═O)—; each of R21 and R22 independently represents a hydrogen atom, a methyl group, etc.; R23 represents —CH2—, —CH(—OH)— or —C(═0)—; and R24 represents a hydrogen atom, a hydroxyl group, a methyl group, etc.
公开/授权文献
- US20130005798A1 ANTIPROTOZOAL COMPOUND DERIVED FROM COELENTERATA 公开/授权日:2013-01-03