发明授权
- 专利标题： Secondary 8-hydroxyquinoline-7-carboxamide derivatives
- 专利标题（中）： 次级8-羟基喹啉-7-甲酰胺衍生物
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申请号： US13519686申请日： 2010-12-28
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公开(公告)号： US08729076B2公开(公告)日： 2014-05-20
- 发明人: Stefania Gagliardi , Simone Del Sordo , Federico Mailland , Michela Legora
- 申请人： Stefania Gagliardi , Simone Del Sordo , Federico Mailland , Michela Legora
- 申请人地址： LU Luxembourg
- 专利权人： Polichem SA
- 当前专利权人： Polichem SA
- 当前专利权人地址： LU Luxembourg
- 代理机构： Hueschen and Sage
- 优先权： EP09180895 20091229
- 国际申请： PCT/EP2010/070793 WO 20101228
- 国际公布： WO2011/080266 WO 20110707
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; A61K31/497 ; A61K31/47 ; C07D403/02 ; C07D413/02 ; C07D215/00
摘要：
The present invention provides new secondary 8-hydroxyquinoline-7-carboxamide derivatives of general formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful as antifungal agents. Specifically, these compounds were tested against Tricophyton Rubrum, Tricophyton Mentagrophytes, Aspergillus Niger and Scopulariopsis Brevicaulis. Many of these compounds are active against Candida species such as Candida Albicans and Candida Glabrata.
公开/授权文献
- US20120316167A1 SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES 公开/授权日：2012-12-13
信息查询
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