发明授权
- 专利标题： Histone demethylase inhibitors and methods for using the same
- 专利标题（中）： 组蛋白脱甲基酶抑制剂及其使用方法
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申请号： US13691507申请日： 2012-11-30
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公开(公告)号： US08735622B2公开(公告)日： 2014-05-27
- 发明人: Xiang Wang , Wenqing Xu
- 申请人： Xiang Wang , Wenqing Xu
- 申请人地址： US CO Denver
- 专利权人： The Regents of the University of Colorado, a body corporate
- 当前专利权人： The Regents of the University of Colorado, a body corporate
- 当前专利权人地址： US CO Denver
- 代理机构： Hamilton DeSanctis & Cha, LLP
- 代理商 Don D. Cha
- 主分类号： C07C271/00
- IPC分类号： C07C271/00
摘要：
The present invention provides compounds, or derivatives or prodrugs thereof, that comprise a methyllysine mimic, and an α-ketoglutarate mimic that are attached through a linker and methods for using and producing the same. In some embodiments, compounds of the invention are of the formula: M-L-K, or a derivative or a prodrug thereof, wherein M is a methyllysine mimic, L is a linker, and K is an α-ketoglutarate mimic.