Invention Grant
US08742089B2 Methods and compositions for expressing negative-sense viral RNA in canine cells
有权
在犬细胞中表达负义病毒RNA的方法和组合物
- Patent Title: Methods and compositions for expressing negative-sense viral RNA in canine cells
- Patent Title (中): 在犬细胞中表达负义病毒RNA的方法和组合物
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Application No.: US13601401Application Date: 2012-08-31
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Publication No.: US08742089B2Publication Date: 2014-06-03
- Inventor: Gregory Duke , George Kemble , James Young , Zhaoti Wang
- Applicant: Gregory Duke , George Kemble , James Young , Zhaoti Wang
- Applicant Address: US MD Gaithersburg
- Assignee: MedImmune, LLC
- Current Assignee: MedImmune, LLC
- Current Assignee Address: US MD Gaithersburg
- Agency: Grant IP, Inc.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/00 ; C12N15/113
Abstract:
The present invention provides novel canine pol I regulatory nucleic acid sequences useful for the expression of nucleic acid sequences in canine cells such as MDCK cells. The invention further provides expression vectors and cells comprising such nucleic acids as well as methods of using such nucleic acids to make influenza viruses, including infectious influenza viruses.
Public/Granted literature
- US20120329150A1 METHODS AND COMPOSITIONS FOR EXPRESSING NEGATIVE-SENSE VIRAL RNA IN CANINE CELLS Public/Granted day:2012-12-27
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