Invention Grant
US08742121B2 Process for the preparation of small molecule inhibitors of MDM2 and intermediates used therein
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制备MDM2的小分子抑制剂的方法及其中使用的中间体
- Patent Title: Process for the preparation of small molecule inhibitors of MDM2 and intermediates used therein
- Patent Title (中): 制备MDM2的小分子抑制剂的方法及其中使用的中间体
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Application No.: US13614751Application Date: 2012-09-13
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Publication No.: US08742121B2Publication Date: 2014-06-03
- Inventor: Shaomeng Wang , Ke Ding , Guoping Wang
- Applicant: Shaomeng Wang , Ke Ding , Guoping Wang
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones, S.C.
- Main IPC: C07D401/02
- IPC: C07D401/02 ; C07D487/10 ; C07D209/04
Abstract:
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
Public/Granted literature
- US20130030173A1 PROCESS FOR THE PREPARATION OF SMALL MOLECULE INHIBITORS OF MDM2 AND INTERMEDIATES USED THEREIN Public/Granted day:2013-01-31
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